Not entirely true: PhotoLine's been on the market for nearly as long as Photoshop, and its layer stack does things that neither Photoshop nor Affinity Photo is capable of. True layer instancing, 'smart objects', each layer can be any resolution, colour mode, and bit depth, mostly non-destructive editing, instancing of layer masks, and more. Arguably of the three, PhotoLine blows both Photoshop and Affinity Photo out of the water in regards to its layer stack.
The layer stack actually reminded me a bit of how C4D does things - extremely modular. Also a German developer, btw.
I switched to PhotoLine for most of my image editing.
You omitted one: Lightwave. It may not have the industry support anymore it used to have, yet it is still a quite capable 3d generalist application. Newtek, however, suffers from the same ailment as MAXON: almost no communication. Lightwave Next ought to be out sometime this year, and will probably add some interesting new features, and a completely overhauled new render engine.
Whether that will be enough...?
Indeed, MAXON cannot rest on their laurels. They did that with BodyPaint (and other modules), and we all know how that panned out. And even Blender is making solid forays into offering better motion graphics tools with "Animation Nodes". Version 2 just added fall-offs to their Effectors - yes, you read that right: the developer took its cue directly from MoGraph's Effectors!
Now, combine this with the upcoming Eevee?